THE EMERGING ROLE OF COMPLEMENT LECTIN PATHWAY IN TRYPANOSOMATIDS: MOLECULAR BASES IN ACTIVATION, GENETIC DEFICIENCIES, SUSCEPTIBILITY TO INFECTION, AND COMPLEMENT SYSTEM-BASED THERAPEUTICS

The innate immune system is evolutionary and ancient and is the pivotal line of the host defense system to protect against invading pathogens and abnormal self-derived components.Cellular and molecular components are involved in recognition and effector mechanisms for a successful innate immune response.The complement lectin pathway (CLP) was disco

This paper presents a software package designed to estimate Poole and Rosenthal W-NOMINATE scores in R.The package uses a logistic regression model to analyze political choice data, usually (though not exclusively) from a legislative setting.In contrast to other scaling methods, W-NOMINATE explicitly assumes probabilistic voting based on a spatial

Introduction: Betaine (trimethyl glycine) is known as methyl group donor and antioxidant in previous reports.The aim of this study was to assess the antioxidant effects of betaine in Indomethacin-induced gastric damages.Methods: Thirty-two adult male Sprague–Dawley rats in an experimental study were divided into four equal groups as follow: C

A long-term goal of AI is to produce agents that can learn a diversity of skills throughout their lifetimes and continuously improve those skills via experience.A longstanding obstacle towards that goal is catastrophic forgetting, which is when learning new information erases previously learned information.Catastrophic forgetting occurs in artifici